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Research

COMPARATIVE EVALUATION OF ANTIOXIDANT POTENTIAL OF EZENUS AND OTHER HERBAL PRODUCTS :

An In Vitro Study by M. Chaudhary and V. Naithani published in World Journal of Pharmacy and Pharmaceutical Sciences

Comparator product details of the Ezenus efficacy study

Code Active ingredients No of constituents Amount of constituent
A Rubia cordifolia, Hemidesmus indicus, Acacia catechu, Azadirachta indica, Curcuma longa, Smilax china, Tinospora cordifolia & Honey 8 260 mg/ml
B Hemidesmus indica, Terminalia chebula, Swertia chirata, Anchrographic paniculata, Rheum emodi & Cassia fistula. 6 375 mg/tablet
C Bauhinia variegata, Canscora decussata, Cassia angustifolia, Chrozophora plicata, Curcuma caesia, Cuscuta reflexa, Dalbergia sissoo, Fumaria parviflora, Ipomoea turpethum, Lavandula stoechas, Melia azadirachta, Nymphaea lotus, Ocimum canum, Pterocarpus santalinus, Rosa damascena, Smilax china, Sphaeranthus indicus, Swertia chirata, Tephrosia purpurea, Terminaliachebula & Tinospora cordifolia 21 10 mg/ml
D Curcuma longa, Cassia fistula, Psoralea corylifolia, Saussurea lappa, Picrorhiza kurroa, Azadirachta indica, Tinospora cordifolia, Crataeva magna, Triphala, Embelia ribes, Eclipta alba & Andrographis paniculata 14 400 mg/tablet
E Embilica officinalis ,Ichnocarpus fructescene, picrorhiza kurroa, Rubia cordifolia, Terminalia Chebula , Crocus sativus, Tinospora cordifolia, Eclipt alba ,Honey, Swertia Chirata & Wheat Germ Oil 11 150 mg/ml
F Picrorhiza kurroa, Boherria diffusa, Andrographis paniculata, Achillea millefolium & Berberis aristata 5 450 mg/ml
G Convolvulus pluricaulus & Centella asiatica 2 26.45 mg/ml
H Withania somnifera, Asparagus adscendens, Rubia cordifolia, Terminalia chebula, Curcuma longa, Berberis aristata, Glycyrrhiza glabra, Pluchea lanceolata, Pueraria tuberosa ,Terminalia arjuna, Cyperus rotundus, Ipomoea turpethum, Hemidesmus indicus, Cryptolepis buchanani, Petrocarpus santalinus, Santalum album, Acorus calamus, Plumbago zeylanica, Woodfordia fruticosa, Honey, Zingiber officinale, Piper nigrum, Piper longum, Cinnamomum zeylanicum, Cinnamomum tamala, Elettaria cardamomum, Callicarpa macrophylla & Mesua ferea 28 34 mg/ml
I Withania somnifera, Valeriana wallichi & Centella asiatica 3 600 mg/capsule
J Withania somnifera 1 500 mg/capsule
K Withania somnifera root extract 1 300 mg/capsule
L Withania somnifera 1 250 mg/capsule
M Andrographis paniculata ext., Boerhaavia diffusa ext.,Tinospora cordifolia ext.& Vitis vinifera ext. 4 42.5 mg/candy
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  • EZENUS (M) has the highest Polyphenol, Flavanoid and Thiol i.e. antioxidant content.
  • EZENUS (M) is the highest in inhibiting Lipid peroxidation and lowering Malondialdehyde content thus demonstrating that it can reduce oxidative stress.
  • EZENUS (M) is most potent in scavenging Superoxide, DPPH and Hydroxyl radicals which are also known as free radicals that damage cells.

EZENUS CLINICAL STUDIES

A DOUBLE BLIND, PLACEBO CONTROLLED, RANDOMIZED STUDY TO ASSESS THE ANTIOXIDANT ACTIVITY OF DIETARY SUPPLEMENT EZENUS IN ADULT HEALTHY SUBJECTS (240)*

*The Clinical Trial was carried out for a period of 30 days. Female subjects were not a part of smoking/alcoholic subject group.

The Clinical Trial was not done on pregnant/lactating women.

  • EZENUS could bring 35 % reduction in MDA level for non-smoking population and 45 % reduction in MDA levels after 30 days for smoking male population.
  • EZENUS could bring upto 35 % reduction F2-Isoprostane levels occurring in the body by virtue of its antioxidant properties for both smoking and non-smoking population.
  • EZENUS could bring upto 50 % elevation in TAC (TOTAL ANTIOXIDANT CAPACITY) levels after 30 days for smoking population.

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